Polarbearmeds - Home

Browse antidepressant medications including SSRIs, SNRIs, atypical antidepressants and tricyclics, with generic equivalents for most brands.

About Depression medications

Antidepressants are grouped by how they act on brain chemistry. SSRIs such as sertraline, escitalopram and fluoxetine are usually tried first. SNRIs such as venlafaxine and duloxetine act on a second neurotransmitter. Atypical options such as bupropion and mirtazapine, and older tricyclics such as amitriptyline, are used when the first choice is not tolerated or not effective.

Most antidepressants take four to six weeks to reach their full effect, and stopping suddenly can cause discontinuation symptoms. Refill on time and talk to your prescriber before making any change.

Antipsychotics, mood stabilisers and anti-anxiety medications are listed separately under Mental Health.

Depression — frequently asked questions

Are generic antidepressants as effective as the brand?
Generic antidepressants contain the same active ingredient at the same strength and must meet the same regulatory standards. Some people notice a difference when switching between manufacturers; mention it to your prescriber or pharmacist if you do.
Can I order a 90-day supply?
Yes, if your prescription authorises that quantity. Larger supplies usually lower your cost per dose and reduce how often you reorder.
Do I need a prescription to order?
Yes. Prescription medications require a valid prescription from your licensed prescriber. After you place your order you can upload, email, fax or mail it to us, and our pharmacy team verifies it before anything ships. Over-the-counter items and supplies do not need a prescription.
How long does delivery take?
Standard delivery to the United States usually takes 2 to 4 weeks from the day your prescription is approved. Expedited shipping is available at checkout, and temperature-sensitive medications ship in cold-chain packaging.

Ordering Depression medications from Polar Bear Meds

We currently list 120 depression products. Every order is dispensed by a licensed pharmacy and shipped to your door in the United States, with our price-match guarantee on every item. Cannot find your medication? Browse all categories, search by drug name, or contact our team and we will source it for you.

This information is provided for general education and does not replace advice from your doctor or pharmacist. Always follow the directions on your prescription.

Price matching guarantee certificate

We offer competitive pricing on all our medications. We'll match if you find a lower price on an identical product at a verified Canadian online pharmacy!

Eligibility Criteria:

  • The competitor's price must be active (no past/future sales).
  • It is only valid for Canadian online pharmacies with a verifiable address.
  • The product must match the strength, pack size, quantity, manufacturer & origin.
  • There are no price matches on used/expired medications.
  • You must submit your requests before placing an order.
  • We cannot adjust prices after purchase.
  • Request via live chat or phone before placing your order.

Need help? Call our friendly support team at 1-888-779-2193 or fill out the Contact Form